职称:教授
职务:
邮箱:hhan@njfu.edu.cn
电话:025-8542-7906
韩晗,教授,博士生导师,硕士生导师,主要研究方向为顶端分生组织内干细胞分化发育的分子机制。谷物、大部分蔬菜水果以及花卉等,都是由植物顶端分生组织的干细胞分化发育而来。这些干细胞是如何保持多能性,以及如何分化发育为成熟的器官是非常重要的科学问题。本课题组主要用分子遗传学、活细胞实时成像、生物化学和计算机模型相结合的方法,研究顶端分生组织内干细胞极性分布和调控花的干细胞分化发育的分子机制。
实验室网页:https://www.x-mol.com/groups/hhan
My research has primarily focused on the molecular mechanisms regulating plant stem cells including the apical-basal patterning of the Shoot Apical Meristem (SAM) and the differentiation of stem cells within the Floral Meristem (FM). A combination of molecular genetics, live cell imaging, biochemical and computational approaches was used to investigate these mechanisms. Because flowers, grains, fruits and seeds are essential SAM products, a detailed understanding of stem cell activities could help address many challenges that we humans face, such as shortages in crop yields and propagation of endangered plant species. My future work is aimed to further probe how stem cells are programmed into organs.
We are recuiting undergraduate, graduate and post-doc research assistants in the lab. Please contact me if you are interested.
学习与工作经历:
2010年本科毕业于首都师范大学生物科学专业,2016年博士毕业于美国南卡大学分子细胞发育生物学专业,之后分别在美国普渡大学和加州河滨分校从事博士后研究,2022年起为南京林业大学生物与环境学院教授。
教学课程:
本科生:《生物显微技术》
留学生:Frontiers in Plant Sciences
课题组成员:
联合培养博士生(1名),联合培养硕士生(4名),本科生(2名)
欢迎对本课题组研究方向感兴趣的本科生,研究生,博士后加入韩老师的研究团队!
主持在研科研项目2项,包括省级人才项目1项和国家级科学项目1项。
Selected publications:
Han, H.*, Yan, A.*, Li, L., Zhu, Y., Liu, X., & Zhou, Y. (2020). A signal cascade originated from epidermis defines apical-basal patterning of Arabidopsis shoot apical meristems. Nature Communications. 11(1), 1-17.
Han, H., Liu, X., & Zhou, Y. (2020). Transcriptional circuits in control of shoot stem cell homeostasis. Current opinion in plant biology, 53, 50-56.
Zhou, Y.*, Yan, A.*, Han, H., Li, T., Geng, Y., Liu, X., & Meyerowitz, E. M. (2018). HAIRY MERISTEM with WUSCHEL confines CLAVATA3 expression to the outer apical meristem layers. Science, 361(6401), 502-506.
Han, H., & Krizek, B. A. (2016). AINTEGUMENTA-LIKE6 can functionally replace AINTEGUMENTA but alters Arabidopsis flower development when misexpressed at high levels. Plant molecular biology, 92(4-5), 597-612.
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